I discovered quickly with Jiggers that he didn't whine in his crate until after he had peed, he didn't like a wet bed. I had to set an alarm so that I could catch him before he went and take him outside, even if that meant waking him up. He was only 6 weeks when I got him so I started with 2 hr intervals and by the time he was 10 weeks he could sleep through the night. I was a zombie for much of that month but he never went in his crate, unless he was sick, again. He even learned that waking me up was the correct action to take if he did need to go.